Amounts used in studies, not a personal plan
Sermorelin Dosage Differed for Each Study Group
Children got one amount; older men got another. See how each drug was given and what changed. These results don't set an amount for you.
The study doses don't set your care
One study gave children a small daily shot under the skin. Another gave older men morning and evening shots for two weeks. Blood cleared sermorelin after about ten minutes, while growth hormone kept rising for about three hours. No proven dose exists for slowing aging in people.
Sermorelin dosage depended on the people studied
Each line describes 1 use in a study. These amounts tell you what researchers did. They aren't a plan for personal use.
- Children whose growth glands made too little hormone: They received 30 micrograms per kilogram a day. A gram is made of one million micrograms. Each child's weight was used to work out the total. The shot went under the skin at bedtime. Growth changed from about 4.1 to about 7-8 cm/year [1].
- Older men: They received 0.5 milligrams or 1 milligram in two shots under the skin each day for 14 days. Blood was drawn many times over each 24-hour day. The bigger amount raised the average growth-hormone level more [2].
- A growth-gland test: Doctors used one dose near 1 microgram per kilogram of the child's weight, given into a vein. The result showed how much hormone the gland could release [7].
- Healthy men: The researchers tried 0.25-2 micrograms per kilogram of each man's weight, given into a vein. Each man's weight set his total amount. The largest hormone rise came at 1-2 micrograms for each kilogram [3].
These are old medical and research amounts, not advice. Powder marked for lab research isn't medicine made for a patient. The figures don't tell you what is safe or useful for you.
Sermorelin half-life means minutes in the blood
Half-life tells you how fast a drug leaves the blood. After a dose into a vein, sermorelin stayed there about 10-12 minutes [3]. Growth hormone remained higher for roughly 3 hours [3]. A nose dose sent only about 3-5% into the blood, so the nose form delivered very little drug [3]. The study didn't test a mouth product.
Scientists made related drugs last longer by helping them cling to blood proteins. CJC-1295 can join to a blood protein named albumin and work for days [15]. Sermorelin can't make that bond. Sermorelin vs CJC-1295 explains the difference in time.
Most studies used shots under the skin
Studies of children and aging used shots just under the skin [1][2]. Growth-gland tests put doses in a vein [3][7]. Nose doses delivered only about 3-5% to the bloodstream [3]. The way the drug entered the body changed how much got into the blood.
Before use, trained staff mix sermorelin powder with a germ-free liquid. The mixed drug can break down and often needs to stay cold. Pharmacy rule 797 calls for trained staff and a work area kept free of dust and germs when sterile drugs are mixed. Even those steps can't make every pharmacy product the same. These facts aren't mixing steps for you to follow.